Thermo Fisher Scientific NBS1 Monoclonal Antibody (1D7)
NBS1 단클론 항체(1D7)는 인간, 마우스, 랫트 반응성을 가지며, WB, ICC/IF, IP 분석에 적합합니다. p95/NBS1 단백질을 표적으로 하며, 단백질 복구 및 세포 주기 연구용으로 사용됩니다. Protein G로 정제된 액상 항체로 장기 보관 시 -20°C에서 안정적입니다.
- 카탈로그번호
- MA123265
- 판매단위
- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1D7 |
| Immunogen | The complete coding region of the human p95/NBS1 expressed in E. coli. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_560310 |
Product Specific Information
Predicted molecular weight: 91 kDa
Positive controls: MCF7, HeLa (NE), Raji
Target Information
The p95 gene (identical to NBS1 and nibrin) is a member of the hMre11/hRad50 double-strand break complex. This protein complex is implicated in Nijmegen breakage syndrome, an autosomal recessive disorder characterized by increased cancer incidence, cell cycle checkpoint deficits, and ionizing radiation sensitivity. It provides a direct molecular link between double-strand break repair and cell cycle checkpoint functions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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