Thermo Fisher Scientific Phospho-BAD (Ser112) Recombinant Rabbit Monoclonal Antibody (BADS112-B9)
Phospho-BAD (Ser112) 표적에 특이적인 재조합 토끼 단클론 항체로, Flow Cytometry에 사용 가능. 높은 특이성과 재현성을 제공하며, 동물 유래 성분이 없는 포뮬레이션. Human, Mouse, Rat 반응성.
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Applications
- Flow Cytometry (Flow)
Tested Dilution: 1–1,000 ng/mL
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | BADS112-B9 |
| Immunogen | Synthetic phospho-peptide corresponding to residues surrounding Ser112 of human phospho BAD |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745048 |
Additional Formats
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. Antibody DNA sequences from immunoreactive rabbits are cloned and screened to select the best candidates for production.
Advantages include:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
The BAD protein belongs to the BCL-2 family, which regulates programmed cell death. It promotes apoptosis by forming heterodimers with BCL-xL and BCL-2, reversing their death repressor activity.
Phosphorylation regulates its proapoptotic activity, involving kinases AKT and MAP kinase, and phosphatase calcineurin.
Alternative splicing generates two transcript variants encoding the same isoform.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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