Thermo Fisher Scientific Lactoferrin Polyclonal Antibody
Lactoferrin 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, Flow Cytometry, ELISA 등에 사용 가능. Human, Mouse, Rat 반응성. Protein A 정제, 1 mg/mL 농도, -20°C 보관. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300 |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Flow Cytometry (Flow) | 1:20–1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human Lactoferrin (amino acids 611–710) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Lactoferrin (LF) is an iron-binding glycoprotein composed of a single polypeptide chain (~80 kDa) folded into two homologous lobes, each capable of reversibly binding one ferric ion (Fe³⁺). It is present in external fluids such as milk and mucosal secretions and is a major component of neutrophil secondary granules. LF plays roles in iron homeostasis regulation, host defense against microbial infections, anti-inflammatory activity, and cellular growth regulation. It has bactericidal and proteolytic properties, capable of cleaving arginine-rich microbial proteins. Three isoforms (LTF-α, LTF-β, LTF-γ) have been identified, and receptors are expressed in the gastrointestinal tract, macrophages, lymphocytes, neutrophils, platelets, and certain bacteria.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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