Thermo Fisher Scientific NUAK2 Polyclonal Antibody
NUAK2 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat에 반응합니다. WB, IHC, ICC, ELISA 등 다양한 응용에 적합하며, Protein A로 정제된 액상 형태입니다. 근육 수축 및 대사 관련 연구에 활용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human NUAK2 (amino acids 31–130) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
NUAK2, also known as SNF1/AMP kinase-related kinase (SNARK), is a member of the NUAK family of SNF1-like kinase 2. It is activated by muscle contraction and mediates contraction-stimulated glucose transport in skeletal muscle. NUAK2 is involved in cellular stress responses linked to obesity and type 2 diabetes. Its kinase activity can be enhanced by AMP and 5-amino-4-imidazolecarboxamide riboside, suggesting activation via AMPK-dependent pathways. Glucose deprivation also increases NUAK2 activity in fibroblasts.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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