Thermo Fisher Scientific MB67 Polyclonal Antibody
Thermo Fisher Scientific의 MB67 Polyclonal Antibody는 Human 및 Mouse 시료에 반응하며 Western blot에 적합합니다. 항원 친화 크로마토그래피로 정제된 Rabbit IgG 항체로, 1 mg/mL 농도의 액상 형태입니다. 약물 대사 관련 핵 수용체 연구에 활용됩니다.
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Applications
- Western Blot (WB): 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment corresponding to a region within amino acids 1–127 of Human NR1I3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2547340 |
Product Specific Information
- Recommended positive control: Mouse liver
- Predicted reactivity: Rat (80%), Rhesus Monkey (96%), Chimpanzee (100%), Bovine (81%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a member of the nuclear receptor superfamily and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or as a heterodimer with the retinoid X receptor, regulating transcription of genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members. Unlike most nuclear receptors, this transcriptional regulator is constitutively active in the absence of ligand but can be modulated by agonists and inverse agonists.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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