Thermo Fisher Scientific XPB Polyclonal Antibody
XPB 단백질을 인식하는 Rabbit Polyclonal Antibody로 인간, 마우스, 랫트에 반응. Western blot, IHC, ICC, ELISA 등 다양한 응용에 적합. Protein A로 정제된 고순도 항체로 안정적인 액상 형태. DNA 복구 및 전사 연구용으로 최적화.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human XPB/ERCC3, amino acids 601–700 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The human XPB DNA helicase is a subunit of the DNA repair/basal transcription factor TFIIH, and is involved in early steps of the nucleotide excision repair (NER) pathway.
Mutations in the XPB gene can lead to clinical phenotypes such as xeroderma pigmentosum associated with Cockayne’s syndrome (XP/CS) and trichothiodystrophy (TTD).
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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