Thermo Fisher Scientific Lipoteichoic Acid Monoclonal Antibody (55)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:50

View 1 publication 1 publication

Immunohistochemistry (Frozen) (IHC (F))

1:50

-

Flow Cytometry (Flow)

1:50

-

ELISA (ELISA)

1:50

-

Product Specifications

Species Reactivity

Bacteria

Published species

Bacteria

Host/Isotype

Mouse / IgG3

Class

Monoclonal

Type

Antibody

Clone

55

Immunogen

Microbial mixture of Streptococcus sobrinus HG961, HG962, HG970, and HG977

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage buffer

tissue culture supernatant

Contains

0.02% sodium azide

Storage conditions

4° C

Shipping conditions

Wet ice

RRID

AB_1076514

Product Specific Information

MA1-40134 detects Lipoteichic Acid from gram positive bacterial samples.

MA1-40134 has been successfully used in Western blot, ELISA, flow cytometry, immunofluorescence, and Immunohistochemistry (frozen) applications.

Positive control: Culture medium of Gram-positive bacteria. Negative control: Culture medium of eukaryotic cells.

The MA1-40134 immunogen is a microbial mixture of Streptococcus sobrinus HG961, HG962, HG970, and HG977.

Target Information

Lipoteichoic acid (LTA) is a glycerol phosphate surface polymer component of the envelope of Gram-positive bacteria. LTA is anchored via its glycolipids to the membrane and carries a polysaccharide chain extending into the peptidoglycan layer of the cell wall. LTA is released spontaneously into the culture medium during growth of gram-positive bacteria. LTA functions as an immune activator with characteristics very similar to lipopolysaccharide (LPS) from Gram-negative bacteria. LTA binds to CD14 and triggers activation predominantly via Toll-like receptor 2. Although LTA is internalized and traffics to the Golgi, the cellular activation in response to LTA occurs at the cell surface.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.