Thermo Fisher Scientific MBL2 Monoclonal Antibody (3E7)

Applications

Tested Dilution

Publications

Immunohistochemistry (Frozen) (IHC (F))

1:50

-

Flow Cytometry (Flow)

1:50

View 5 publications 5 publications

ELISA (ELISA)

1:50

-

Functional Assay (Functional)

1:50

-

in situ PLA (PLA)

-

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human

Published species

Human, Rhesus monkey, Yeast

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

3E7

Immunogen

Serum isolated human RaRF if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MBL2,uniProtId:P11226-1,ncbiNodeId:9606,antigenRange:1-248,antigenLength:248,antigenImageFileName:MA1-40145_MBL2_P11226-1_House_mouse.svg,antigenImageFileNamePDP:MA1-40145_MBL2_P11226-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Protein G

Storage buffer

PBS with 0.1% BSA

Contains

no preservative

Storage conditions

4° C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_1076469

Product Specific Information

MA1-40145 detects MBL from human samples.

The MA1-40145 immunogen is Mannose Binding Lectin (MBL).

MA1-40145 has been successfully used in flow cytometry, Western blot, ELISA, Functional Assays, and immunohistochemistry (frozen) applications.

Negative control: Nonimmune normal serum or TBS.

Endotoxin <24 EU/mg.

Target Information

MBL2 is a calcium-dependent lectin involved in innate immune defense. It binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. It also binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. MBL2 may bind DNA.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.