Thermo Fisher Scientific Phospho-Neurofibromin (Ser2741) Polyclonal Antibody
인간 Neurofibromin Ser2741 인산화 부위를 인식하는 Rabbit Polyclonal 항체로, WB 및 IHC(P)에서 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태이며, 0.5 mg/mL 농도. 연구용으로만 사용 가능.
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Thermo Fisher Scientific Phospho-Neurofibromin (Ser2741) Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide surrounding the epitope -PTSPY- with a phosphorylation site of Ser2741 of human neurofibromin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 25 mM Tris with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: Mouse hypoxic brain
Target Information
The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments.
The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells.
Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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