
Thermo Fisher Scientific CD105 Recombinant Rabbit Monoclonal Antibody (103)
CD105(Endoglin)에 특이적인 재조합 토끼 모노클로날 항체로, 인간 시료에 반응합니다. ICC/IF 및 유세포분석(Flow Cytometry)에 적합하며, 높은 특이성과 로트 간 일관성을 제공합니다. 보존제가 없는 액상형 제품으로 단기 4°C, 장기 -20°C 보관 권장.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:20–1:100
Flow Cytometry (Flow)
- Tested Dilution: 1:25–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 103 |
| Immunogen | Recombinant Human Endoglin/CD105 protein (Met1–Gly586) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2785134 |
Additional Formats
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide (final concentration 0.05%–0.1%) to avoid contamination.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select optimal candidates for production.
Advantages:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal-origin-free formulation
- Broader immunoreactivity due to larger rabbit immune repertoire
This antibody has specificity for Human Endoglin/CD105.
Target Information
CD105 (Endoglin) is a Type I transmembrane protein highly expressed on human vascular endothelial cells. It forms an O- and N-glycosylated homodimer. Upregulation of CD105 expression is observed in tumor vasculature and proliferating cells, indicating its role as a proliferation-associated endothelial marker. CD105 binds to TGF-β1 and TGF-β3 with high affinity but not to TGF-β2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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