Thermo Fisher Scientific B4GALT4 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 35-344 of human B4GALT4 (NP_0037691) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:B4GALT4,uniProtId:O60513-1,ncbiNodeId:9606,antigenRange:35-344,antigenLength:344,antigenImageFileName:PA5-89987_B4GALT4_O60513-1_Rabbit.svg,antigenImageFileNamePDP:PA5-89987_B4GALT4_O60513-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.48 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2805877

Product Specific Information

Immunogen sequence: VGAIQEIPKA KEFMANFHKT LILGKGKTLT NEASTKKVEL DNCPSVSPYL RGQSKLIFKP DLTLEEVQAE NPKVSRGRYR PQECKALQRV AILVPHRNRE KHLMYLLEHL HPFLQRQQLD YGIYVIHQAE GKKFNRAKLL NVGYLEALKE ENWDCFIFHD VDLVPENDFN LYKCEEHPKH LVVGRNSTGY RLRYSGYFGG VTALSREQFF KVNGFSNNYW GWGGEDDDLR LRVELQRMKI SRPLPEVGKY TMVFHTRDKG NEVNAERMKL LHQVSRVWRT DGLSSCSYKL VSVEHNPLYI NITVDFWFGA; Positive Samples: 293T, HT-29, Mouse kidney, Mouse thymus, Mouse lung, Rat kidney, Rat thymus, Rat lung; Cellular Location: Golgi apparatus, Golgi stack membrane, Single-pass type II membrane protein

Target Information

This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene appears to mainly play a role in glycolipid biosynthesis. Two alternatively spliced transcript variants have been found for this gene.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.