
Thermo Fisher Scientific DARPP-32 Polyclonal Antibody
Rabbit polyclonal antibody recognizing DARPP-32 for human, mouse, and rat. Suitable for WB and ICC/IF applications. Affinity purified and unconjugated. Supplied in PBS with glycerol and BSA; store at 4°C or -20°C. Research use only.
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Applications
Western Blot (WB)
- Tested Dilution: 1–2 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:250
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Protein corresponding to Human PPP1R1B (aa 1–204) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 30% glycerol, 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2633201 |
Product Specific Information
These polyclonal antibodies are of rabbit origin, developed by immunizing animals with proteins or peptides. The antibody is purified by affinity chromatography from rabbit sera and tested for functionality in relevant research applications.
This product is intended for Research Use Only and is non-hazardous and non-infectious in nature.
This antibody is predicted to react with Monkey, Pig, Horse, and Cat.
Target Information
DARPP-32 is a dopamine (DA) and AMP-regulated ~32 kDa phosphoprotein associated with dopaminoceptive neurons. When phosphorylated on Thr34, it inhibits Protein Phosphatase I; when phosphorylated on Thr75, it inhibits PKA. Phosphorylation of DARPP-32 plays a critical role in dopaminergic neurotransmission and is implicated in the actions of alcohol, caffeine, and Prozac®.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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