Thermo Fisher Scientific SMN1 Polyclonal Antibody
Rabbit polyclonal antibody targeting Human SMN1 protein (aa 2-294). Suitable for WB and ICC/IF applications. Purified by affinity chromatography, supplied as liquid form in PBS buffer. For research use only.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Protein corresponding to Human SMN1 (aa 2–294) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.1% BSA, 30% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2633202 |
Product Specific Information
These polyclonal antibodies are of rabbit origin, developed by immunizing animals with proteins or peptides. The antibody is purified by affinity chromatography from rabbit sera and tested for functionality in various research applications.
Developed for Research Use Only and is non-hazardous or non-infectious in nature.
Predicted to react with Monkey, Pig, and Cat.
Target Information
The SMN1 gene is part of a 500 kb inverted duplication on chromosome 5q13 containing multiple genes and repetitive elements, making it prone to rearrangements and deletions.
The telomeric and centromeric copies encode the same survival motor neuron protein, which plays a catalytic role in assembling small nuclear ribonucleoproteins, essential components of the spliceosome.
Mutations in SMN1 cause spinal muscular atrophy types 1 and 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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