Thermo Fisher Scientific AHCY Recombinant Rabbit Monoclonal Antibody (4E9H10)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1 µg/mL

-

Immunoprecipitation (IP)

0.5 µg-4 µg antibody for 200 µg-400 µg extracts of

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

4E9H10

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 300-400 of human AHCY (P23526). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:AHCY,uniProtId:P23526-1,ncbiNodeId:9606,antigenRange:300-400,antigenLength:432,antigenImageFileName:MA5-42797_AHCY_P23526-1_Rabbit.svg,antigenImageFileNamePDP:MA5-42797_AHCY_P23526-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.33 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2911938

Product Specific Information

Positive test controls include: HT-29, HepG2, A375, K-562, Mouse pancreas, Mouse liver, Mouse kidney, Rat kidney. The target is usually found in the following locations: Cytoplasm, Melanosome.

Immunogen sequence: GHFDVEIDVK WLNENAVEKV NIKPQVDRYR LKNGRRIILL AEGRLVNLGC AMGHPSFVMS NSFTNQVMAQ IELWTHPDKY PVGVHFLPKK LDEAVAEAHL G

Target Information

S-adenosylhomocysteine hydrolase (AHCY) catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). Thus, it regulates the intracellular S-adenosylhomocysteine (SAH) concentration thought to be important for transmethylation reactions. Deficiency in this protein is one of the different causes of hypermethioninemia. S-adenosylhomocysteine hydrolase belongs to the adenosylhomocysteinase family.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.