Thermo Fisher Scientific Phospho-HIPK1/HIPK2/HIPK3 (Tyr352, Tyr361, Tyr359) Polyclonal Antibody
HIPK1/2/3 단백질의 Tyr352/361/359 인산화 형태를 특이적으로 인식하는 rabbit polyclonal 항체. Western blot 및 IHC(P) 검증 완료. 인간, 마우스, 랫트 반응성. 1 mg/mL 액상, PBS(50% glycerol) 버퍼, -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human HIPK1 (Accession Q86Z02), corresponding to amino acid residues around phosphorylated Tyr352. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2817286 |
Product Specific Information
Antibody detects endogenous levels of HIPK1/2/3 only when phosphorylated at Tyr352/361/359.
Target Information
The protein encoded by this gene belongs to the Ser/Thr family of protein kinases and HIPK subfamily. It phosphorylates homeodomain transcription factors and may also function as a co-repressor for homeodomain transcription factors. Alternative splicing results in four transcript variants encoding four distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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