
Thermo Fisher Scientific Phospho-EphA2 (Tyr588) Polyclonal Antibody
인간, 생쥐, 랫트에서 인산화된 EphA2(Tyr588)을 특이적으로 검출하는 Rabbit IgG 폴리클로날 항체입니다. Western blot 및 IHC(파라핀 절편)에 적합하며, 순차 크로마토그래피로 정제된 액상 형태입니다. PBS/glycerol 버퍼에 보관하며 -20°C에서 안정적입니다.
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Thermo Fisher Scientific Phospho-EphA2 (Tyr588) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human EPHA2 (Accession P29317), corresponding to amino acid residues around phosphorylated Tyr588 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816976 |
Product Specific Information
Antibody detects endogenous levels of EPHA2 only when phosphorylated at Tyr588.
Target Information
EPHA2 belongs to the ephrin receptor subfamily of the protein tyrosine kinase family. EPH and EPH-related receptors are involved in developmental events, particularly in the nervous system. EPHA2 is overexpressed in many types of human cancers. The tyrosine kinase (TK) group regulates cell-cell interactions such as differentiation, adhesion, motility, and death. Approximately 90 TK genes have been sequenced, including 58 receptor TKs (e.g., EGFR, EPH, FGFR, PDGFR, TRK, VEGFR families) and 32 cytosolic TKs (e.g., ABL, FAK, JAK, SRC families).
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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