Thermo Fisher Scientific KLK8 Monoclonal Antibody (OTI6D6), TrueMAB
Human KLK8 단백질(아미노산 33-260)을 인식하는 마우스 단클론 항체로, Western blot에 최적화됨. TrueMAB 형식의 고순도 항체이며, 동결건조 형태로 제공. 연구용으로 암 관련 바이오마커 연구에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6D6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 33–260 of human KLK8 produced in SF9 cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of about 1 mg/mL.
For conjugation experiments, perform another round of desalting (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Kallikreins are a subgroup of serine proteases with diverse physiological functions. Many kallikreins are implicated in carcinogenesis and may serve as biomarkers for cancer and other diseases.
KLK8 is one of fifteen kallikrein subfamily members located in tandem on chromosome 19. The encoded protein may be involved in proteolytic cascades in the skin and may serve as a biomarker for ovarian cancer.
Alternate splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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