Thermo Fisher Scientific PLOD2 Monoclonal Antibody (OTI6D1), TrueMAB
인간 PLOD2 단백질을 표적으로 하는 마우스 단클론 항체로, WB 및 IHC(P) 응용에 적합합니다. 고순도 친화 크로마토그래피 정제 제품이며, 동결건조 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific PLOD2 Monoclonal Antibody (OTI6D1), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-Dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6D1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 359–640 of human PLOD2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The PLOD2 gene encodes a membrane-bound homodimeric enzyme localized to the cisternae of the rough endoplasmic reticulum. It catalyzes hydroxylation of lysyl residues in collagen-like peptides, forming hydroxylysyl groups essential for collagen stability and crosslinking.
Deficiencies in lysyl hydroxylase activity are linked to Ehlers-Danlos syndrome type VIB and Bruck syndrome. Alternative splicing produces multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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