Thermo Fisher Scientific KLK8 Monoclonal Antibody (OTI11C3), TrueMAB
Human KLK8 단백질을 표적으로 하는 Mouse IgG1 단클론 항체로, WB 및 IHC(P) 응용에 적합. 고순도 친화 크로마토그래피로 정제된 동결건조형 제품이며, 보존제 무첨가 PBS 버퍼에 8% 트레할로스 포함. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI11C3 |
| Immunogen | Human recombinant protein fragment (amino acids 33–260 of human KLK8) produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Kallikreins are a subgroup of serine proteases with diverse physiological functions.
Many kallikreins are implicated in carcinogenesis and have potential as cancer or disease biomarkers.
KLK8 is part of a gene cluster on chromosome 19 and may play a role in proteolytic cascades in the skin, serving as a potential biomarker for ovarian cancer.
Alternate splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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