Thermo Fisher Scientific CAMK2B Monoclonal Antibody (OTI8D9), TrueMAB
CAMK2B 단백질을 인식하는 마우스 단클론 항체로, Western blot 및 IHC(P) 적용 가능. 인간, 마우스, 랫트 반응성. 동결건조 형태로 제공되며, PBS 버퍼에 보존. 신경계 연구 및 단백질 발현 분석에 적합.
- 판매단위
- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8D9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 311–385 of human CAMK2B produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
CAMK2B (CaMKII beta) is a serine/threonine kinase involved in synaptic plasticity, synaptic vesicle mobilization, and regulation of gene expression. As a dominant kinase in the central nervous system, it may contribute to long-term potentiation and neurotransmitter release.
There are four CaMKII isozymes (alpha, beta, gamma, delta) that may be co-expressed in various tissues. CaMKII alpha undergoes autophosphorylation on Thr286 upon Ca2+/CaM complex binding to its autoinhibitory domain, a process known as Ca2+/CaM trapping, which is implicated in synaptic information encoding.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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