Thermo Fisher Scientific CAMK2B Monoclonal Antibody (OTI8D9), TrueMAB

Applications

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

CAMK2B (CaMKII beta) is a serine/threonine kinase involved in synaptic plasticity, synaptic vesicle mobilization, and regulation of gene expression. As a dominant kinase in the central nervous system, it may contribute to long-term potentiation and neurotransmitter release.
There are four CaMKII isozymes (alpha, beta, gamma, delta) that may be co-expressed in various tissues. CaMKII alpha undergoes autophosphorylation on Thr286 upon Ca2+/CaM complex binding to its autoinhibitory domain, a process known as Ca2+/CaM trapping, which is implicated in synaptic information encoding.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

(해당 항체 및 항원 관련 이미지는 Thermo Fisher Scientific 제공 자료 참조)