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Thermo Fisher Scientific CD11b Monoclonal Antibody (M1/70), Brilliant Violet 421, eBioscience

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Mouse CD11b 검출용 단클론 항체(M1/70)로 Brilliant Violet 421 형광 표지. 유세포분석(Flow Cytometry)에 최적화되어 있으며, 0.125 µg/test 권장. Mac-1 복합체 인식, 다양한 면역세포 표면 CD11b 검출에 사용. 4°C 암소 보관, 동결 금지.

카탈로그번호: 404-0112-8x (2개 옵션)
브랜드: Thermo Fisher Scientific
카테고리: Monoclonal Antibodies
판매단위: pk

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마지막 업데이트 2025. 08. 04. 오후 05:57

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Thermo Fisher Scientific 404-0112-82 CD11b Monoclonal Antibody (M1/70), Brilliant Violet 421, eBioscience 100 ug pk판매 단위 pk ·

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583,600원VAT 포함 641,960원

Thermo Fisher Scientific 404-0112-80 CD11b Monoclonal Antibody (M1/70), Brilliant Violet 421, eBioscience 25 ug pk판매 단위 pk ·

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235,600원VAT 포함 259,160원

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Thermo Fisher Scientific · Thermo Fisher Scientific CD11b Monoclonal Antibody (M1/70), Brilliant Violet 421, eBioscience

Applications and Tested Dilution

Application: Flow Cytometry (Flow)
Tested Dilution: 0.125 µg/test
Publications: View 1 publication

Product Specifications

항목	내용
Species Reactivity	Mouse
Published Species	Not Applicable
Host / Isotype	Rat / IgG2b, kappa
Recommended Isotype Control	Rat IgG2b kappa Isotype Control (eB149/10H5), Brilliant Violet™ 421, eBioscience™
Class	Monoclonal
Type	Antibody
Clone	M1/70
Conjugate	Brilliant Violet™ 421
Excitation / Emission Max	406 / 423 nm
Form	Liquid
Concentration	0.2 mg/mL
Purification	Affinity chromatography
Storage Buffer	PBS, pH 7.2, with BSA
Contains	0.09% sodium azide
Storage Conditions	4°C, store in dark, DO NOT FREEZE
Shipping Conditions	Ambient (domestic); Wet ice (international)
RRID	AB_2925490

Available Formats

Unconjugated
Alexa Fluor 488, 532, 660, 700
APC, APC-eFluor 780
Biotin
Brilliant UV 395–805
Brilliant Violet 480–786
eFluor 450, 506, 660
FITC
Functional Grade
NovaFluor Blue/Yellow series
PE, PE-Cyanine5, PE-Cyanine7, PE-eFluor 610
PerCP-Cyanine5.5, PerCP-eFluor 710
Super Bright 436–780
Request custom conjugation

Product Specific Information

Description:
The M1/70 monoclonal antibody reacts with mouse CD11b (integrin alphaM, 165–170 kDa). CD11b associates with CD18 to form the alphaMbeta2 integrin (Mac-1), binding CD54 (ICAM-1), C3bi, and fibrinogen. It is expressed by macrophages, NK cells, granulocytes, activated lymphocytes, and peritoneal B-1 cells. M1/70 cross-reacts with human CD11b and can detect this antigen on human monocytes, granulocytes, and NK cell subsets. CD11b plays a role in adhesive cell interactions.

Applications Reported: Flow cytometric analysis.
Applications Tested: Tested on mouse bone marrow cells; ≤0.125 µg/test recommended (100 µL final volume). Optimize empirically for each assay.

Fluorochrome Information:
Brilliant Violet™ 421 (BV421) emits at 423 nm, excited by a 405 nm violet laser. Ensure instrument compatibility.

Buffer Recommendations:
When using multiple polymer dye-conjugated antibodies (Super Bright, Brilliant Violet™, Brilliant UV™, etc.), use:

Super Bright Complete Staining Buffer (#SB-4401-42)
or Brilliant Stain Buffer™ (#00-4409-75)
to minimize non-specific interactions.

Excitation: 407 nm
Emission: 423 nm
Laser: Violet Laser

BRILLIANT VIOLET™ is a trademark of Becton, Dickinson and Company. Powered by Sirigen™.

Target Information

CD11b (integrin alpha-M, ITGAM, integrin alpha-X, ITGAX) is a 165 kDa adhesion molecule forming a heterodimer with CD18 (integrin beta-2). The CD11b/CD18 complex (Mac-1, CR3) binds ICAM-1, ICAM-2, ICAM-4, CD14, CD50, CD23, heparin, iC3b, fibrinogen, and Factor X, mediating cell-cell and cell-matrix interactions.

CD11b is expressed on: