Thermo Fisher Scientific CSK Polyclonal Antibody
Rabbit Polyclonal Anti-CSK 항체로 Western blot 및 Immunoprecipitation에 적합. 인간 C-src Tyrosine Kinase의 400–450번 잔기 영역을 면역원으로 사용. 액상 형태, 1 mg/mL 농도, 4°C 보관. 세포 성장과 신호 조절 연구용.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 400 to 450 of human C-src Tyrosine Kinase |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
CSK is a tyrosine kinase that downregulates SRC oncoprotein activity through phosphorylation of its carboxy terminus. Since cell transformation by SRC is caused by mechanisms interfering with this phosphorylation, the CSK gene may function as an antioncogene. CSK regulates cell growth, differentiation, migration, and immune responses. It phosphorylates tyrosine residues in the C-terminal tails of Src-family kinases including LCK, SRC, HCK, FYN, LYN, CSK, and YES1. CSK is ubiquitously expressed as a ~50 kDa cytosolic protein, with a fraction localized to lipid rafts via interaction with PAG (Csk-binding protein).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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