Thermo Fisher Scientific SDCCAG8 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Protein corresonding to Human SDCCAG8. Recombinant protein control fragment (Product #RP-105761). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SDCCAG8,uniProtId:Q86SQ7-1,ncbiNodeId:9606,antigenRange:358-453,antigenLength:713,antigenImageFileName:PA5-110911_SDCCAG8_Q86SQ7-1_Rabbit.svg,antigenImageFileNamePDP:PA5-110911_SDCCAG8_Q86SQ7-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2856322

Product Specific Information

Immunogen sequence: LIQCDQLRKE LERQAERLEK ELASQQEKRA IEKDMMKKEI TKEREYMGSK MLILSQNIAQ LEAQVEKVTK EKISAINQLE EIQSQLASRE MDVTKV

Target Information

SDCCAG8 (serologically defined colon cancer antigen 8), also known as CCCAP (centrosomal colon cancer autoantigen protein), HSPC085 or NY-CO-8, is a 713 amino acid cytoplasmic protein that is expressed in thymus, prostate, testis, ovary, small intestine, colon, mucosa and renal cancer tumors. Existing as a homodimer, SDCCAG8 localizes to centrioles and interacts with oral-facial-digital syndrome 1 (ODF1), which is associated with nephronophthisis-related ciliopathies (NPHP-RC), a recessive disorder that is characterized by dysplasia or degeneration of the kidney, retina and cerebellum. SDCCAG8 exists as four alternatively spliced isoforms and is encoded by a gene located on humanc chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.