Thermo Fisher Scientific MTBP Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Protein corresonding to Human MTBP. Recombinant protein control fragment (Product #RP-93903). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MTBP,uniProtId:Q96DY7-1,ncbiNodeId:9606,antigenRange:602-693,antigenLength:904,antigenImageFileName:PA5-110909_MTBP_Q96DY7-1_Rabbit.svg,antigenImageFileNamePDP:PA5-110909_MTBP_Q96DY7-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2856320

Product Specific Information

Immunogen sequence: DAKELLKYFT SDGLPIGDLQ PLPIQKGEKT FVLTPELSPG KLQVLPFEKA SVCHYHGIEY CLDDRKALER DGGFSELQSR LIRYETQTTC TR

Target Information

MTBP inhibits cell migration in vitro and suppresses the invasive behavior of tumor cells. The protein may play a role in MDM2-dependent TP53/p53 homeostasis in unstressed cells. The protein inhibits autoubiquitination of MDM2, thereby enhancing MDM2 stability. This promotes MDM2-mediated ubiquitination of TP53/p53 and its subsequent degradation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.