Thermo Fisher Scientific CD62L (L-Selectin) Monoclonal Antibody (MEL-14), FITC, eBioscience

Thermo Fisher Scientific CD62L (L-Selectin) Monoclonal Antibody (MEL-14), FITC, eBioscience

Applications and Tested Dilution

Product Specifications

Available Formats

• Alexa Fluor 561
• Alexa Fluor 700
• APC
• APC-eFluor 780
• Biotin
• Brilliant UV 395, 496, 615, 737, 805
• Brilliant Violet 421, 480, 605, 650, 786
• eFluor 450
• Functional Grade
• NovaFluor Blue 510, 555, 585, 610-30S, 660-40S
• NovaFluor Red 710
• NovaFluor Yellow 590, 660
• PE, PE-Cyanine5, PE-Cyanine7, PE-eFluor 610
• PerCP-Cyanine5.5
• Super Bright 436, 600, 702, 780
• Custom conjugation available upon request

Product Specific Information

The MEL-14 monoclonal antibody reacts with mouse CD62L, a 76 kDa member of the selectin family. CD62L is expressed by neutrophils, monocytes, and subsets of T, B, and NK cells. It binds glycosylated, fucosylated, sulfated sialylated glycoproteins such as CD34, glycam-1, and MAdCam-1, mediating lymphocyte rolling on activated endothelium and homing to high endothelial venules (HEV) of peripheral lymphoid tissues.

• Applications Reported: Flow cytometric analysis
• Applications Tested: Tested on mouse splenocytes at ≤0.5 µg/test (100 µL final volume).
  Recommended careful titration for optimal performance.
• Excitation: 488 nm
• Emission: 520 nm
• Laser: Blue Laser
• Filtration: 0.2 µm post-manufacturing filtered

Target Information

Human CD62L (L-Selectin) is a 74–95 kDa glycoprotein adhesion receptor. It includes:

• Aminoterminal C-type lectin binding domain
• EGF-like domain
• Two short consensus repeat sequences (SCR)
• Spacer, transmembrane, and cytoplasmic regions

CD62L is constitutively expressed on most leukocytes including lymphocytes (except many memory T cells), monocytes, and polymorphonuclear cells.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지