Thermo Fisher Scientific PDCD2 Polyclonal Antibody
PDCD2 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot 및 Immunoprecipitation에 적합. 항원 친화 크로마토그래피로 정제되었으며, 4°C에서 보관. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 294 and 344 of human Programmed Cell Death 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
Essential component of an SCF-type E3 ligase complex, SCF(NIPA), which controls mitotic entry by mediating ubiquitination and degradation of cyclin B1 (CCNB1). Its phosphorylation regulates the SCF(NIPA) complex assembly, restricting CCNB1 ubiquitination to interphase. Inactivation leads to nuclear accumulation of CCNB1 and premature mitotic entry. May have an antiapoptotic role in NPM-ALK-mediated signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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