Thermo Fisher Scientific TACR1 Polyclonal Antibody
인간 NK1 수용체를 검출하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(Paraffin) 실험에 적합합니다. 합성 펩타이드 면역원 기반으로 제작되었으며, -20°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:5,000 | - |
| Immunohistochemistry (IHC) | - | 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000 | - |
| Immunocytochemistry (ICC/IF) | - | 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues S(387)-S(407) of human NK1 receptor protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2200607 |
Product Specific Information
PA3-301 detects neurokinin-1 receptor in human samples.
It has been successfully used in Western blot and immunohistochemistry (paraffin) procedures.
The immunogen is a synthetic peptide corresponding to residues S(387)-S(407) of human NK1 receptor protein.
Target Information
Tachykinin Receptor 1 (TACR1), a member of the Tachykinin Receptor subfamily, mediates phosphatidylinositol metabolism via the tachykinin substance P (neurokinin 1).
It is associated with depression, anxiety, and stress regulation, as well as neuronal survival and cardiovascular/respiratory functions.
TACR1 is implicated in the progression of rheumatoid arthritis and osteoarthritis.
Two variants are produced by alternative splicing.
Expression is mainly observed in brain, blood lymphocytes, nose, small intestine, and stomach. ESTs have been isolated from brain and spleen libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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