
Thermo Fisher Scientific NTSR2 Polyclonal Antibody
Rabbit polyclonal antibody against human NTSR2 receptor. Validated for Western blot and paraffin IHC. Detects ~55–60 kDa NTS2 protein. Supplied as liquid whole serum with sodium azide, store at -20°C. For research use only.
- 카탈로그번호
- PA3300
- 판매단위
- pk
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2 µg/mL | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues P(381) Q S P T L M D T A S G F G D P P E T R T(401) of human NTS2 receptor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2236334 |
Product Specific Information
PA3-300 detects neurotensin receptor NTS2 from human samples.
It has been successfully used in Western blot and immunohistochemistry (paraffin) applications.
By Western blot, this antibody detects a ~55–60 kDa protein representing the NTS2 receptor.
The immunogen is a synthetic peptide corresponding to residues P(381)–T(401) of human NTS2 receptor.
Target Information
The protein encoded by this gene belongs to the G protein-coupled receptor family that activates a phosphatidylinositol-calcium second messenger system.
Binding and pharmacological studies demonstrate that this receptor binds neurotensin as well as several other ligands described for the neurotensin NT1 receptor.
Unlike the NT1 receptor, this gene recognizes, with high affinity, levocabastine, a histamine H1 receptor antagonist that competes with neurotensin for low-affinity binding sites in the brain.
These activities suggest that this receptor may be of physiological importance and that a natural agonist for the receptor may exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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