Thermo Fisher Scientific Erythropoietin (EPO) Monoclonal Antibody (EPO, 1367)

Applications

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 2–4 µg/mL
• Publications: [참고 문헌 없음]

Peptide Array (Array)

• Tested Dilution: Assay-dependent
• Publications: [참고 문헌 없음]

Product Specifications

Product Specific Information

• Immunohistochemistry (PFA fixed):
  Incubate antibody for 30 min at room temperature (RT).
  Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris Buffer with 1 mM EDTA (pH 9.0) for 45 min at 95°C, followed by cooling at RT for 20 min.

Target Information

Erythropoietin (EPO) protein is a growth factor essential for the survival, proliferation, and differentiation of erythroid precursors.
EPO induces the final maturation of partially differentiated erythroid cells and promotes production of red cell-specific proteins such as hemoglobin.
The EPO receptor (EPOR) is highly expressed on precursor cells and decreases as cells mature.
During fetal development, hepatocytes are the main source of EPO; after birth, renal interstitial cells become the primary source.
EPO expression increases under hypoxic conditions and may also contribute to neuronal protection and repair.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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