Thermo Fisher Scientific Versican Recombinant Rabbit Monoclonal Antibody (6D8K9)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:2,000

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

6D8K9

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 3200-3396 of human Versican (P13611). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Versican,uniProtId:P13611-1,ncbiNodeId:9606,antigenRange:3200-3396,antigenLength:3396,antigenImageFileName:MA5-42721_Versican_P13611-1_Rabbit.svg,antigenImageFileNamePDP:MA5-42721_Versican_P13611-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.4 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 0.05% BSA, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2911862

Product Specific Information

Immunogen sequence: QGAHLTSILS HEEQMFVNRV GHDYQWIGLN DKMFEHDFRW TDGSTLQYEN WRPNQPDSFF SAGEDCVVII WHENGQWNDV PCNYHLTYTC KKGTVACGQP PVVENAKTFG KMKPRYEINS LIRYHCKDGF IQRHLPTIRC LGNGRWAIPK ITCMNPSAYQ RTYSMKYFKN SSSAKDNSIN TSKHDHRWSR RWQESRR

Target Information

Versican is a member of the family of large aggregating proteoglycans (also including aggrecan, brevican, and neurocan). The protein shows wide tissue distribution which includes fibrous, articular, and elastic cartilages, as well as nervous, epidermal, arterial, and loose connective tissues. Versican V1 has been shown to enhance cell proliferation, and also induce cell transformation and protect cells from apoptosis. This was demonstrated through its ability to downregulate the expression of proapoptotic Bad. Versican`s existence as a extracellular matrix protein in human airways has also lead to the discovery of an inflammatory role in asthmatics.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.