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Thermo Fisher Scientific IFN gamma Monoclonal Antibody (4S.B3), PE, eBioscience
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IFN gamma를 인식하는 4S.B3 단클론 항체로, PE 형광체가 결합된 Flow Cytometry용 항체입니다. 인간 세포 내 IFNγ 분석에 적합하며, 488–561 nm 레이저로 여기됩니다. 4°C 암소 보관, 동결 금지.
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- 12-7319-4x (2개 옵션)
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- pk
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Thermo Fisher Scientific 12-7319-42 IFN gamma Monoclonal Antibody (4S.B3), PE, eBioscience 100 tests pk판매 단위 pk ·
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442,900원VAT 포함 487,190원
Thermo Fisher Scientific 12-7319-41 IFN gamma Monoclonal Antibody (4S.B3), PE, eBioscience 25 tests pk판매 단위 pk ·
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181,900원VAT 포함 200,090원
Thermo Fisher Scientific · Thermo Fisher Scientific IFN gamma Monoclonal Antibody (4S.B3), PE, eBioscience
Thermo Fisher Scientific IFN gamma Monoclonal Antibody (4S.B3), PE, eBioscience™
Applications and Tested Dilution
- Application: Flow Cytometry (Intracellular)
- Tested Dilution: 5 µL (0.125 µg)/test
- Publications: View 105 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Mouse, Rhesus monkey |
| Host / Isotype | Mouse / IgG1, kappa |
| Recommended Isotype Control | Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), PE, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4S.B3 |
| Conjugate | PE |
| Excitation/Emission Max | 565/576 nm |
| Form | Liquid |
| Concentration | 5 µL/Test |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 0.2% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1311250 |
Available Formats
- Unconjugated
- Alexa Fluor 488
- Alexa Fluor 660
- Alexa Fluor 700
- APC
- APC-eFluor 780
- Biotin
- Brilliant UV 395 / 496 / 615 / 661 / 737 / 805
- Brilliant Violet 650
- eFluor 450 / 506 / 660
- FITC
- PE-Cyanine7
- PE-eFluor 610
- PerCP-Cyanine5.5
- Request custom conjugation
Product Specific Information
The 4S.B3 monoclonal antibody reacts with interferon-gamma (IFNγ), a 17 kDa cytokine produced by activated T and NK cells with antiviral and antiparasitic activity. IFNγ synergizes with TNFα to inhibit proliferation of normal and transformed cells and exerts immunomodulatory effects on various cell types expressing IFNγ receptors. Glycosylation does not affect its biological activity.
- Applications Reported: Intracellular flow cytometric analysis
- Applications Tested: Pre-titrated and tested by flow cytometry on activated human cells
- Recommended Usage: 5 µL (0.125 µg) per test in 100 µL final volume (10⁵–10⁸ cells/test)
- Excitation/Emission: 488–561 nm / 578 nm
- Compatible Lasers: Blue, Green, Yellow-Green
- Filtration: 0.2 µm post-manufacturing filtered
Target Information
IFN gamma (Interferon gamma, Type II interferon):
- Macrophage activation factor produced mainly by T-lymphocytes and NK cells
- Dimeric glycoprotein (~45 kDa) composed of two 146 amino acid subunits
- Exhibits antiviral, antitumor, and immunomodulatory functions
- Induces MHC class I/II expression and enhances B cell immunoglobulin secretion
- Acts via IFNγ receptor I/II and JAK-STAT signaling
- Human IFNγ shows ~40% sequence homology with mouse IFNγ and is species-specific
- Upregulated by IL2, FGF basic, EGF; downregulated by vitamin D3 or DMN
- Mutations associated with aplastic anemia
For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.
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