Thermo Fisher Scientific GM-CSF Monoclonal Antibody (MP1-22E9), PE, eBioscience
마우스 GM-CSF를 인식하는 중화 단일클론 항체로, PE 형광체 결합 제품입니다. 세포내 유세포분석(Flow Cytometry)에 적합하며, 488–561 nm 여기 파장에서 사용 가능합니다. 0.2 mg/mL 농도의 액상 형태로 제공되며, 4°C 암소 보관 권장.
- 카탈로그번호
- 12-7331-8x (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific GM-CSF Monoclonal Antibody (MP1-22E9), PE, eBioscience
Thermo Fisher Scientific GM-CSF Monoclonal Antibody (MP1-22E9), PE, eBioscience™
Applications and Tested Dilution
- Application: Flow Cytometry (Intracellular Staining)
- Tested Dilution: ≤ 0.25 µg/test
(A test is defined as the amount of antibody that will stain a cell sample in 100 µL final volume. Cell number: 10⁵–10⁸ cells/test.)
Publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Mouse |
| Host / Isotype | Rat / IgG2a, kappa |
| Recommended Isotype Control | Rat IgG2a kappa Isotype Control (eBR2a), PE, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MP1-22E9 |
| Conjugate | PE (R-Phycoerythrin) |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic), Wet ice (international) |
| RRID | AB_466204 |
| Filtration | 0.2 µm post-manufacturing filtered |
Additional Formats
- Unconjugated
- APC
- FITC
- Functional Grade
- PE-Cyanine7
- Custom conjugation available
Product Specific Information
The MP1-22E9 antibody reacts with mouse granulocyte/macrophage colony-stimulating factor (GM-CSF).
It is a neutralizing antibody that recognizes GM-CSF, a 14 kDa factor mainly produced by activated T cells and macrophages.
Other cell types such as endothelium and fibroblasts also secrete GM-CSF in response to TNF-α, IL-2, IL-1, and IFN-γ.
GM-CSF promotes the growth of macrophages, granulocytes, and dendritic cells, existing in both membrane-bound and extracellular matrix-associated forms.
Non-glycosylated GM-CSF retains biological activity.
Applications Reported: Intracellular flow cytometric analysis
Applications Tested: Intracellular staining and flow cytometric analysis of cultured mouse splenocytes
Recommended Excitation/Emission: 488–561 nm / 578 nm
Compatible Lasers: Blue, Green, Yellow-Green
Target Information
The GM-CSF gene encodes a cytokine that regulates the production, differentiation, and function of macrophages and granulocytes.
The active form exists as a homodimer in the extracellular space.
Located on chromosome region 5q31, this gene cluster is associated with interstitial deletions in 5q- syndrome and acute myelogenous leukemia.
Other genes in the cluster include IL-4, IL-5, and IL-13.
The gene is involved in promoting tissue inflammation.
Elevated levels of GM-CSF have been observed in SARS-CoV-2 patients with acute respiratory distress syndrome.
Mice lacking this gene or its receptor develop pulmonary alveolar proteinosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.