Thermo Fisher Scientific Phospho-FLNC 2233 (Ser2233) Polyclonal Antibody
인간, 마우스, 랫트 반응성을 가진 FLNC Ser2233 인산화 특이성 폴리클로날 항체입니다. IHC(P), IHC(F), ICC/IF 등 다양한 면역염색 응용에 적합하며, 높은 특이성과 안정성을 제공합니다. 단백질 A 정제, 액상 형태로 -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic phosphopeptide derived from human FLNC around the phosphorylation site of Ser2233 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes one of three related filamin genes, specifically gamma filamin. These filamin proteins crosslink actin filaments into orthogonal networks in cortical cytoplasm and participate in anchoring membrane proteins to the actin cytoskeleton.
Three functional domains exist in filamin:
- N-terminal filamentous actin-binding domain
- C-terminal self-association domain
- Membrane glycoprotein-binding domain
Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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