Thermo Fisher Scientific FLNB/Filamin 3 Polyclonal Antibody
FLNB/Filamin 3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF, ELISA 등 다양한 응용에 적합. 인간, 마우스, 랫트 반응성. Protein A 정제 및 고농도(1 mg/mL) 액상 형태로 제공.
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Thermo Fisher Scientific FLNB/Filamin 3 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:400 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human FLNB/Filamin 3, amino acids 1551–1650 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
FOXK1 is expressed in these cells and regulates cell cycle progression through an interaction with its downstream target, the cyclin-dependent kinase inhibitor p21 (CIP). Loss of FOXK1 in mice results in growth retardation and severe impairment in skeletal muscle regeneration following injury. FOXK1 also shows expression in immature tissues of brain, eye, heart, lung, and thymus. It is predominantly expressed in many malignant tissues, such as tumors of the brain, colon, and lymph node.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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