Thermo Fisher Scientific CD34 Chimeric Recombinant Rabbit Monoclonal Antibody (2E 10)
CD34 단백질을 인식하는 재조합 토끼 단일클론 항체로, 인간 시료에 반응합니다. Western blot, ICC/IF, Flow cytometry 등 다양한 분석에 사용됩니다. 고순도 Protein A 정제, 1 mg/mL 농도, 장기 보관 시 -20°C 권장.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | 1:1,000 |
| Flow Cytometry (Flow) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 2E 10 |
| Immunogen | The antibody was raised by repeatedly immunising BALB/c mice with KG-1a cells. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
Product Specific Information
This antibody is specific to a class III epitope on CD34, which is not susceptible to cleavage by neuraminidase, chymopapain, or glycoprotease.
Target Information
CD34 is a highly glycosylated monomeric surface protein (111–115 kDa) expressed on many stem cell populations. It serves as a stem cell marker with reversible expression in human hematopoietic stem cells. CD34 may function as a surface receptor involved in receptor-mediated endocytosis and regulation of adhesion, differentiation, and proliferation of hematopoietic stem cells and progenitors. It is also thought to mediate attachment to the bone marrow extracellular matrix or stromal cells, potentially acting as a scaffold for lineage-specific glycans. CD34 can present carbohydrate ligands to selectins and may play a role in signal transduction via phosphorylation by activated protein kinase C. Diseases associated with CD34 dysfunction include dermatofibrosarcoma and neurofibroma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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