Thermo Fisher Scientific NRIP Polyclonal Antibody
Thermo Fisher Scientific의 NRIP Polyclonal Antibody는 인간 NRIP 단백질을 타겟으로 하는 Rabbit IgG 항체입니다. Western blot, IHC, IP 등 다양한 응용에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 4°C에서 보관하며 연구용으로 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (IHC) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 |
| Immunoprecipitation (IP) | 10–15 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 300 and 350 of human nuclear receptor interaction protein (IQ motif and WD repeats 1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC: Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
- Based on 100% sequence identity, this antibody is predicted to react with Mouse and Orangutan
Target Information
NRIP is a novel 860 amino acid nuclear protein consisting of seven conserved WD40 domains and one NLS motif. It binds to androgen and glucocorticoid receptors and upregulates their transcriptional activity, functioning as a nuclear receptor coactivator. NRIP is implicated in cell growth and in cervical and prostate cancer, suggesting therapeutic potential. Northern blot analysis shows high expression in skeletal muscle and testis, and low expression in heart, prostate, and adrenal gland.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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