
Thermo Fisher Scientific Rb1 Polyclonal Antibody
Rb1 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot 및 Immunoprecipitation에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태. 인간 Rb 단백질(550–600 aa) 부위를 면역원으로 사용. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: Assay-dependent
Immunoprecipitation (IP)
- Tested Dilution: 10–15 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 550 and 600 of Human retinoblastoma 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
Rb (Retinoblastoma protein) is a tumor suppressor nuclear phosphoprotein capable of binding to DNA. It is phosphorylated on serine and threonine residues and forms complexes with SV40 large T antigen, adenovirus E1A, and human papilloma virus-16 E. Rb protein regulates transcription, and loss of its function can lead to uncontrolled cell growth. Mutations or aberrations in the RB gene are associated with cancers such as breast, colon, prostate, kidney, nasopharyngeal carcinoma, and leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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