Thermo Fisher Scientific NRIP Polyclonal Antibody
Thermo Fisher Scientific의 NRIP Polyclonal Antibody는 인간 NRIP 단백질을 인식하는 토끼 IgG 항체로, WB, IHC, IP 등에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 4°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunoprecipitation (IP) | 10–15 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 600 and 650 of human nuclear receptor interaction protein (IQ motif and WD repeats 1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Target Information
NRIP is a novel 860 amino acid nuclear protein consisting of seven conserved WD40 domains and one NLS motif. It binds to androgen and glucocorticoid receptors and upregulates their transcriptional activity, functioning as a nuclear receptor coactivator. NRIP is implicated in cell growth and in cervical and prostate cancer, indicating potential therapeutic relevance.
Northern Blot analysis shows high expression in skeletal muscle and testis, and low expression in heart, prostate, and adrenal gland.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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