Thermo Fisher Scientific Phospho-SMAD3 (Ser423) Polyclonal Antibody
SMAD3 단백질의 Ser423 인산화 형태를 특이적으로 검출하는 Rabbit Polyclonal 항체. Western Blot 및 Immunocytochemistry에 적합. 인간, 생쥐, 랫트 반응성. 액상 형태, 1 mg/mL 농도, PBS/glycerol buffer에 보관. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
- Publications: 참고 문헌 보기
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
- Publications: 참고 문헌 보기
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SMAD3 (Accession P84022), corresponding to amino acid residues around phosphorylated Ser423 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2817552 |
Product Specific Information
Antibody detects endogenous levels of Smad3 only when phosphorylated at Ser423.
Target Information
SMAD3 belongs to the SMAD family of proteins. They are similar to the gene products of the Drosophila gene mothers against decapentaplegic (Mad) and the C. elegans gene Sma.
SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways.
This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-106154_SMAD3_P84022-1_Rabbit.svg, PA5-106154_SMAD3_P84022-1_Rabbit_PDP.jpeg)
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