Thermo Fisher Scientific CaMKII alpha/delta Polyclonal Antibody
CaMKII alpha/delta 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC/IF에 적합합니다. Human, Mouse, Rat 시료에 반응하며, 고순도 친화 크로마토그래피로 정제되었습니다. -20°C에서 보관하며 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CAMK2A (Accession Q9UQM7), corresponding to amino acid residues A262–N312 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899573 |
Product Specific Information
This antibody detects endogenous levels of total CaMKII alpha/delta.
Target Information
The Ca²⁺/calmodulin-dependent protein kinases (CaM kinases) form a subfamily of serine/threonine kinases that includes CaMKI, CaMKII, and CaMKIV. CaMKII is a ubiquitously expressed kinase activated by Ca²⁺ and calmodulin (CaM), involved in regulating the cell cycle and transcription. There are four CaMKII isozymes—alpha, beta, gamma, and delta—which may be co-expressed in the same tissue. CaMKII alpha undergoes autophosphorylation on Thr286 upon Ca²⁺/CaM binding, a process known as Ca²⁺/CaM trapping, thought to play a role in synaptic information encoding.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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