Thermo Fisher Scientific Blood Group ABH Antigen Monoclonal Antibody (HE-10)
혈액형 관련 ABH 항원 인식용 단클론 항체로, 인간 시료에 반응하며 악성 조직에서 특이적 반응을 보임. IHC 및 유세포분석 등 다양한 면역학적 응용에 적합. 비결합형 액상 형태로 4°C 보관.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Flow Cytometry (Flow)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgM |
| Class | Monoclonal |
| Type | Antibody |
| Clone | HE-10 |
| Immunogen | Mixture of erythrocytes from saliva of secretors with blood group A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Buffer | Tissue culture supernatant |
| Contains | No preservative |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1070768 |
Product Specific Information
This antibody reacts with A and H antigens with chain types 3 and 4 and does not react with A disaccharide, A trisaccharide, A type 1, A type 2, ALe-b.
The antibody HE-10 does not react with normal tissue sections of donors with blood group B and O, but it reacts specifically with malignant tissue.
Target Information
Blood-group antigens are molecules formed by sequential addition of saccharides to carbohydrate side chains of lipids and proteins found on erythrocytes and certain epithelial cells.
The A, B, and H antigens undergo modulation during malignant cellular transformation.
Blood group-related antigens represent carbohydrate determinants carried on both glycolipids and glycoproteins, typically mucin-type, detected on erythrocytes, epithelial cells, and in secretions of certain individuals.
Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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