Thermo Fisher Scientific CACNB1 Polyclonal Antibody
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Thermo Fisher Scientific의 CACNB1 Polyclonal Antibody는 인간, 마우스, 랫트에 반응하며 Western blot 및 IHC에 적합합니다. 동결건조 형태로 제공되며, 장기 보관 시 -20°C에서 안정적입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Goat / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the N-terminal region of mouse CACNB1 (CAB1) conjugated to an immunogenic carrier protein was used as the antigen. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- The peptide shares 98% identity with rat and human sequences.
- Specificity of this antibody: CACNB1
Target Information
Calcium Channel 1 is a protein encoded by the CACNB1 gene and belongs to the calcium channel beta subunit family.
It plays a critical role in calcium channel function by:
- Modulating G protein inhibition
- Increasing peak calcium current
- Controlling alpha-1 subunit membrane targeting
- Shifting voltage dependence of activation and inactivation
Dysfunction of this protein is associated with malignant hyperthermia susceptibility.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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