
Thermo Fisher Scientific CLCKB Polyclonal Antibody
CLCKB 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot 및 IHC에 사용 가능. Rat 종에 반응하며, 합성 펩타이드 항원을 사용해 제작됨. 동결건조 형태로 제공되며, 4°C 또는 -20°C에서 보관 권장. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the N-terminal region of rat Chloride channel protein ClC-Kb (CLCKB) conjugated to an immunogenic carrier protein. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: CLCKB.
Target Information
Chloride channel Kb (CLCNKB) is a member of the CLC family of voltage-gated chloride channels, which includes at least nine mammalian chloride channels. These channels are believed to have 12 transmembrane domains and intracellular N- and C-termini.
Mutations in CLCNKB cause autosomal recessive Type III Bartter Syndrome. CLCNKA and CLCNKB are closely related (94% sequence identity), tightly linked (separated by 11 kb of genomic sequence), and both are expressed in mammalian kidney.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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