Thermo Fisher Scientific XPB Polyclonal Antibody
Recombinant Human XPB 항원을 면역원으로 한 Rabbit Polyclonal Antibody. 인간 XPB 단백질 검출용으로 ICC/IF에 적합. 항원 친화 크로마토그래피로 정제되었으며, 0.1 mg/mL 농도의 액상 형태. 4°C 단기 보관 또는 -20°C 장기 보관 권장.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human XPB. Recombinant protein control fragment (Product #RP-106107) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2662641 |
Product Specific Information
Immunogen sequence:
KLCTVSYGKVK LVLKHNRYFV ESCHPDVIQH LLQDPVIREC RLRNSEGEAT ELITETFTSK SAISKTAESS GGPSTSRVTD PQGKSDIPMD LFDFYEQMDK DEEEEE
- Highest antigen sequence identity to the following orthologs:
- Mouse: 90%
- Rat: 90%
Target Information
The human XPB DNA helicase is a subunit of the DNA repair/basal transcription factor TFIIH and is involved in early steps of the nucleotide excision repair (NER) pathway.
Mutations in the XPB gene can result in clinical phenotypes such as xeroderma pigmentosum associated with Cockayne’s syndrome (XP/CS) and trichothiodystrophy (TTD).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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