Thermo Fisher Scientific COLQ Polyclonal Antibody
Rabbit polyclonal antibody targeting human COLQ protein for ICC/IF applications. Recognizes recombinant human COLQ with high specificity. Supplied as liquid, unconjugated form, purified by antigen affinity chromatography. Ideal for research use in neur...
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Applications
- Immunocytochemistry (ICC/IF): 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human COLQ. Recombinant protein control fragment (Product #RP-106100). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2665190 |
Product Specific Information
Immunogen sequence:
PPGRCLCGPTM NVNNPSYGES VYGPSSPRVP VIFVVNNQEE LERLNTQNAI AFRRDQRSLY FKDSLGWLPI QLTPFYPVDY TA
Highest antigen sequence identity to the following orthologs:
- Mouse: 89%
- Rat: 84%
Target Information
COLQ (collagen-like tail subunit of asymmetric acetylcholinesterase) is a 455 amino acid protein localized at the skeletal muscle end plate. It anchors catalytic subunits of AChE to the basal lamina at vertebrate neuromuscular junctions.
Mutations in COLQ cause congenital myasthenic syndromes—rare autosomal recessive diseases characterized by muscle weakness, ophthalmoplegia, and resistance to anticholinesterase drugs.
Eight isoforms exist due to alternative splicing.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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