Thermo Fisher Scientific TCR V beta 9 Monoclonal Antibody (AMKB1-2), PE, eBioscience
인간 TCR Vβ9을 인식하는 AMKB1-2 단클론 항체로, PE 형광표지되어 Flow Cytometry 분석에 최적화됨. 5 µL/test로 사용 가능하며, 488–561 nm 레이저에 적합. 자가면역 및 T세포 클론성 연구에 활용 가능.
- 카탈로그번호
- 12-4899-42
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific TCR V beta 9 Monoclonal Antibody (AMKB1-2), PE, eBioscience
Thermo Fisher Scientific TCR V beta 9 Monoclonal Antibody (AMKB1-2), PE, eBioscience
Applications
- Flow Cytometry (Flow)
Tested Dilution
- 5 µL (0.125 µg)/test
Publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Mouse |
| Host / Isotype | Mouse / IgG1, kappa |
| Recommended Isotype Control | Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), PE |
| Class | Monoclonal |
| Type | Antibody |
| Clone | AMKB1-2 |
| Conjugate | PE |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Concentration | 5 µL/test |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 0.2% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10668006 |
Additional Formats
Product Specific Information
This AMKB1-2 monoclonal antibody recognizes the human T cell receptor (TCR) Vβ9 allele.
TCR specificity is determined by Valpha, Jalpha, Vbeta, Dbeta, and Jbeta gene rearrangement.
Vβ expression has been studied in relation to superantigens, inflammation, autoimmune disease, and HIV infection.
It is used to phenotype T cell clonality in CD3⁺/TCRαβ⁺ large granular lymphocyte leukemias.
This receptor, a member of the Ig superfamily, is expressed on a subset of peripheral blood T cells.
Applications Reported: Flow cytometric analysis
Applications Tested: Pre-titrated for flow cytometry on normal human peripheral blood cells.
Use at 5 µL (0.125 µg) per test (100 µL final volume).
Cell number range: 10⁵–10⁸ cells/test.
Excitation: 488–561 nm; Emission: 578 nm; Laser: Blue, Green, Yellow-Green.
Filtration: 0.2 µm post-manufacturing filtered.
Target Information
T cell receptors (TCRs) discriminate foreign from self-peptides presented by MHC class II molecules, critical for adaptive immune responses.
Self-peptide recognition is linked to autoimmune disease, while mutant self-peptides are associated with tumors.
Superantigen engagement of TCRs can cause toxic shock syndrome.
Autoantibodies to Vβ segments have been found in RA and SLE patients, potentially modulating TH1-mediated inflammation.
Most human T cells express TCR αβ and either CD4 or CD8; a small subset lacks both (double negative).
Gamma-delta T cells, found mainly in epithelia, show limited diversity and distinct antigen recognition, with antitumor and immunoregulatory activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.