Thermo Fisher Scientific ADAMTS8 Polyclonal Antibody

Applications and Tested Dilutions

Product Specifications

Product Specific Information

• In direct ELISAs, approximately 5% cross-reactivity with recombinant human (rh) ADAMTS1 is observed.
• Less than 1% cross-reactivity with rhADAMTS1, rhADAMTS3, rhADAMTS4, rhADAMTS5, rhADAMTS10, rhADAMTS12, rhADAMTS13, and rhADAMTS16 is observed.
• Reconstitute in sterile PBS to a final concentration of 0.2 mg/mL.

Target Information

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of this family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif.
Individual members differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs and disrupts angiogenesis in vivo. A number of disorders have been mapped in the vicinity of this gene, most notably lung neoplasms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.