
Thermo Fisher Scientific TROP2 Polyclonal Antibody
TROP2 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체. Western blot, IHC, ICC, Flow cytometry 등 다양한 응용 가능. 인간 시료 반응성, 항원 친화 크로마토그래피로 정제. 연구용 전용 제품으로 높은 특이성과 재현성 제공.
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Thermo Fisher Scientific TROP2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1 µg/mL | - |
| Immunohistochemistry (IHC) | - | 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–15 µg/mL | - |
| Immunocytochemistry (ICC/IF) | 2 µg/mL | - |
| Flow Cytometry (Flow) | 2.5 µg per million cells | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human TROP-2 (Thr88–Thr274) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2609571 |
Product Specific Information
- In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant human MCAM, NCAM-L1, and BCAM is observed.
- Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
TROP2 is a carcinoma-associated antigen defined by the monoclonal antibody GA733. This antigen belongs to a family of type I membrane proteins and functions as a cell surface receptor that transduces intracellular calcium signals. Mutations in the TROP2 gene can cause gelatinous drop-like corneal dystrophy, an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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