Thermo Fisher Scientific NME1 Monoclonal Antibody (OTI1H4), TrueMAB
인간 NME1 단백질에 특이적인 Mouse IgG2b 단일클론 항체로 Western blot과 IHC(P) 적용 가능. 무보존제, Lyophilized 형태로 제공되며 재구성 후 1 mg/mL 농도 유지. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1H4 |
| Immunogen | Full length human recombinant protein of human NME1 produced in E.coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
NME1 was identified due to reduced mRNA transcript levels in highly metastatic cells.
Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of A (encoded by NME1) and B (encoded by NME2) isoforms.
Mutations in NME1 are associated with aggressive neuroblastomas.
Two transcript variants encoding different isoforms have been found.
Co-transcription of NME1 and NME2 generates naturally occurring fusion transcripts encoding a protein sharing sequence identity with both gene products.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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