Thermo Fisher Scientific NME1 Monoclonal Antibody (OTI22E1), TrueMAB

Applications

• Western Blot (WB): Tested dilution 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

NME1 was identified due to reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of A (encoded by this gene) and B (encoded by NME2) isoforms. Mutations in this gene are associated with aggressive neuroblastomas. Two transcript variants encoding different isoforms have been identified. Co-transcription of NME1 and the neighboring NME2 gene produces naturally occurring NME1-NME2 fusion transcripts encoding a protein sharing sequences from both gene products.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.